LETTER TO THE EDITOR METALLIC COPPER DECREASES RAT UTERINE PROGESTERONE RECEPTOR COl\1'ENT AND PROGESTERONE BINDING
نویسنده
چکیده
The mechanism by which metaillic copper increases efficacy of an intrauterine contraceptive device sti II remains unclear. Copper has strong affinity for progesterone receptors and consequently inh ibits progestationa I oro Iifer3tion (5). However, the change was observed on Iy in the cytosol fraction of the rabbit uterus and no estimate of the effect of copper on nuclear receptors and the translocation process was Available. file have therefore investigated these events in the rat uterus,
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